◀ Back to IRF6

EIF2AK2 — IRF6

Text-mined interactions from Literome

Goh et al., EMBO J 2000 : Using embryonic fibroblasts from PKR wild-type and null mice, we established a requirement for PKR in the activation of SAPKs by double stranded RNA, lipopolysaccharide (LPS) and proinflammatory cytokines
Gon et al., Clin Exp Allergy 2005 (Hypersensitivity) : Furthermore, we found that protein kinase R (PKR) was activated by LPS in these cells
Yoshida et al., J Cell Biochem 2012 (Periodontitis) : These results indicated that LPS induces PKR phosphorylation and the PACT-PKR association in Sa3 cells
Mecha et al., Cell death & disease 2012 (Inflammation) : Indeed, CBD diminished the phosphorylation of PKR and eiF2a induced by LPS/IFN?
Li et al., Mol Med 2013 : It was previously unknown whether panx-1 channel blockers can abrogate lipopolysaccharide (LPS) induced PKR activation and HMGB1 release in innate immune cells ... As did P2X7R antagonists ( for example, oxidized ATP, oATP ), CBX also effectively attenuated LPS induced P2X7R/panx-1 channel activation ( as judged by Lucifer Yellow dye uptake ) and PKR phosphorylation in primary peritoneal macrophages
Gusella et al., J Immunol 1995 (Mast-Cell Sarcoma) : LPS induced PKR expression in a dose dependent manner at levels that were comparable with those observed in response to IFNs