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DUSP1 — IL8
Text-mined interactions from Literome
King et al., J Biol Chem 2009
:
Adenoviral expression of
MKP-1 profoundly
reduces p38 MAPK phosphorylation and
IL-8 expression ... Thus,
MKP-1 attenuates TNFalpha dependent activation of p38 MAPK, induction of
IL-8 expression, and NF-kappaB dependent transcription
Turpeinen et al., J Pharmacol Exp Ther 2010
:
In the present study, we investigated the
effect of
MKP-1 on the expression of interleukin (IL)-6,
IL-8 and cyclooxygenase (COX)-2 in response to stimulation with cytokines ( tumor necrosis factor, IL-1beta, and interferon-gamma ; 10 ng/ml each ) in A549 human lung epithelial cells ... Down-regulation of
MKP-1 with small interfering RNA enhanced p38 and JNK phosphorylation and
increased IL-6,
IL-8 , and COX-2 expression in A549 cells
Kjellerup et al., Br J Dermatol 2013
(Dermatitis, Atopic...) :
In NHEKs,
interleukin (IL)-1ß induced
DUSP1 mRNA expression in a rapid and time dependent manner through the p38 MAPK/mitogen- and stress activated kinase ( MSK ) signalling pathway