Gene interactions and pathways from curated databases and text-mining

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IRF6 — LPO

Text-mined interactions from Literome

Cheng et al., Shock 2005 : Lead ( Pb ) increases lipopolysaccharide (LPS) induced tumor necrosis factor-alpha (TNF-alpha), nitric oxide ( NO ), lipid peroxidation (LPO) , and liver damage ... Pb + LPS coexposure significantly increased phosphorylation of p42/44 MAPK and TNF-alpha expression in peripheral blood cells ; however, exposure to Pb + LPS did not induce TNF-alpha, NO, or LPO production and p42/44 MAPK activation in the liver
Escames et al., Exp Gerontol 2006 (Endotoxemia...) : An age dependent increase in iNOS activity, NO content, and LPO levels was observed, and these changes were augmented further by LPS
Sewerynek et al., J Physiol Pharmacol 2011 : We have found that LPS induces LPO in tissue homogenates in vitro in a concentration dependent manner, the concentration of 400 µg/ml demonstrating the most efficient lipid damaging effect ... The aim of our study was to compare the effects of melatonin (MEL) and indole compound : 6-methoxytryptophol, on LPS induced LPO in vitro ... In all the examined tissues, LPS stimulated LPO , while both melatonin and 6-methoxytryptophol released LPS stimulated LPO