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HMGA1 — INSR

Text-mined interactions from Literome

Brunetti et al., FASEB J 2001 : Using a conventional chromatographic purification procedure combined with electrophoresis mobility shift assay and immunoblot analyses, a unique approximately 15 kDa protein, either identical to or highly related to the architectural transcription factor HMGI(Y), has now been identified, suggesting an essential role for HMGI(Y) in regulating insulin receptor gene transcription ... In these experiments, antisense HMGI(Y) specifically inhibits insulin receptor promoter function and insulin receptor protein expression, indicating that HMGI(Y) is required for proper transcription of insulin receptor gene
Kolb et al., Cancer Res 2007 (Pancreatic Neoplasms) : HMGA1 controls transcription of insulin receptor to regulate cyclin D1 translation in pancreatic cancer cells
Chiefari et al., Scientific reports 2012 : In the present study, we investigated whether activation of the INSR by insulin affected HMGA1 protein phosphorylation and its regulation of gene transcription