◀ Back to RELA
PDLIM2 — RELA
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Tanaka et al., Nat Immunol 2007
:
Here we report that
PDLIM2 negatively
regulated NF-kappaB activity, acting as a nuclear ubiquitin E3 ligase targeting the p65 subunit of NF-kappaB
Healy et al., J Leukoc Biol 2009
:
Suppression of
PDLIM2 expression in THP-1 and RAW 264.7 cells
resulted in decreased adhesion, increased
NF-kappaB transcription reporter activity, and increased LPS induced TNF-alpha production
Qu et al., Cancer Res 2010
(Colorectal Neoplasms) :
Indeed, expression of exogenous
PDLIM2 inhibited constitutive
NF-kappaB activation in these colorectal cancer cells