◀ Back to RELA
RELA — UCN
Text-mined interactions from Literome
Yeow et al., Br J Cancer 2006
(Neoplasms) :
The weak VA-mediated induction of apoptosis of thoracic cancer cells can be profoundly enhanced either by Parthenolide, a pharmacologic
inhibitor of
NF-kappaB , or by
UCN-01 a kinase inhibitor that has already undergone phase I clinical development
Huang et al., J Mol Endocrinol 2009
:
Urocortin induces interleukin-6 release from rat cardiomyocytes through p38 MAP kinase, ERK and
NF-kappaB activation ...
Ucn also
activates nuclear factor kappa B (NF-kappaB) and a NF-kappaB inhibitor blocks Ucn induced IL-6 release ... Finally, the CRH-R antagonists alpha-helical ( 9-41 ) CRH and astressin-2B completely inhibit
Ucn induced IL-6 release, as well as activation of ERK, p38, and
NF-kappaB