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EPHB2 — NEUROD4

Text-mined interactions from Literome

Ghil et al., J Neurochem 2000 : Thus, activation of Erk may not be essential for neuronal differentiation in F11 cells and alphao may cause changes in NOG by inhibiting CREB activation
Olsson et al., Exp Cell Res 2000 (Neuroblastoma) : However, activation and nuclear accumulation of ERK were not sufficient to induce neuronal differentiation in SH-SY5Y, as demonstrated by the response to TPA in serum-free cultures
Harada et al., Nat Cell Biol 2001 : In PC12 cells, sustained activation of ERK induced by nerve-growth factor (NGF) is essential for neuronal differentiation
Hansen et al., Neurosci Lett 2003 : The results demonstrate that PKA and ERK play a key role in KCl- and forskolin induced neuronal differentiation by integration of signals from both pathways
Hetman et al., Eur J Biochem 2004 (MAP Kinase Signaling System) : In the nervous system, ERK1/2 is critical for neuronal differentiation , plasticity and may also modulate neuronal survival
Lee et al., J Neurochem 2004 (Neuroblastoma) : Our results suggest that ERK1/2 and PKA induced regulation of Cdk5 activity possibly through Egr-1, c-fos, and CREB plays a critical role in the RA-induced neuronal differentiation
Katakowski et al., Neurosci Lett 2005 : EphB2 transiently down-regulated SVZ cell mRNA of Notch1 and Zic1, genes that regulate neurogenesis and neuronal differentiation
Kim et al., Toxicology 2007 (Neuroblastoma) : Thus, it indicates that the neuronal differentiation with RA was mediated by the ERK1/2 and PKC related pathway and MeHg resulted in neurotoxic influences through the disturbance in steps of differentiation by this pathway
Rudolph et al., Biochim Biophys Acta 2007 (MAP Kinase Signaling System) : Rit mutants confirm role of MEK/ERK signaling in neuronal differentiation and reveal novel Par6 interaction
Yang et al., J Biol Chem 2008 (MAP Kinase Signaling System) : Basic fibroblast growth factor induced neuronal differentiation of mouse bone marrow stromal cells requires FGFR-1, MAPK/ERK , and transcription factor AP-1
Wang et al., Neurosci Lett 2009 : We also found that nerve growth factor (NGF) and collagen could promote the proliferation and inhibit neuronal differentiation by activating phosphorylation of Erk1/2
Washio et al., Exp Cell Res 2009 : Our findings indicate that HA inhibits NGF induced neuronal differentiation of PC12 cells partially by inhibiting ERK phosphorylation through RHAMM, and suggest that the binding of HA to RHAMM modifies the signaling pathways in PC12 cells treated with NGF
Marcucci et al., J Biol Chem 2010 : Both PtdCho biosynthesis and neuronal differentiation are dependent on ERK activation
Pan et al., J Biol Chem 2012 : Moreover, neurotrophins including NT3 activate ERK5 and stimulate neuronal differentiation in aNPCs in an ERK5 dependent manner
Shi et al., PloS one 2012 (MAP Kinase Signaling System) : Further characterization indicated that ZEL-H16 behaved as a partial agonist on the inhibition of forskolin stimulated cAMP accumulation ( the efficacy was 60 % of that of histamine ) and activation of ERK1/2 signaling ( the efficacy was 50 % of that of histamine ) at H3 receptors, but acted as a full agonist just like histamin in the guinea-pig ileum contraction assay
Lonic et al., J Biol Chem 2013 (MAP Kinase Signaling System) : The regulation of Ras and ERK signaling by Ser ( 779 ) was critical not only for neuronal differentiation but also for cell survival under limiting growth factor concentrations
Li et al., Toxicological sciences : an official journal of the Society of Toxicology 2013 : Furthermore, inhibition of ERK5 signaling may underlie the adverse effect of 6-OH-PBDE-47 on proliferation and neuronal differentiation
Yao et al., J Biol Chem 1998 : Induction of neuronal differentiation of the rat pheochromocytoma cell line, PC12 cells, by nerve growth factor (NGF) requires activation of the mitogen activated protein ( MAP ) kinase or extracellular signal regulated kinase ( ERK )