Gene interactions and pathways from curated databases and text-mining

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ADAMTS4 — EPHB2

Text-mined interactions from Literome

Sylvester et al., Cell Signal 2004 : ERK pathway inhibitors, PD98059 and U0126, down-regulated IL-17 induced MMP and ADAM-TS4 gene expression
El Mabrouk et al., Biochim Biophys Acta 2007 : These results suggest that OSM stimulated ADAMTS-4 and MMP-13 expression is mediated by ERK1/2 , JAK3/STAT1/3 and PI3K/Akt and by cross talk between these pathways
Sylvester et al., Cell Physiol Biochem 2012 : These results suggest partial involvement of ERK- , p38-and JNK-MAPKs as well as AP-1, ATF-2 and NF-?B transcription factors in IL-1 induced ADAMTS-4 in chondrocytes
Wei et al., Spine (Phila Pa 1976) 2013 : Gene expression of ADAMTS-4, ADAMTS-5 , and TGF-b were not affected by IL-1 or ERK inhibition ... Gene expression of ADAMTS-4 , ADAMTS-5, and TGF-b were not affected by IL-1 or ERK inhibition