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IL7 — RAG2

Text-mined interactions from Literome

Wang et al., J Clin Invest 2008 : Expression of RAG was specific to antigen-reactive B cells, required the function of the IL-7 receptor (IL-7R) , and contributed to maintenance of humoral tolerance
Appasamy et al., J Exp Med 1993 : We also show that IL-7 induced RAG-1 and RAG-2 mRNA expression by FL cells
Melamed et al., J Immunol 1997 : In contrast, we found that IL-7 inhibited maturation of non-Tg B cell precursors and that removal of IL-7 resulted in a significant increase in RAG-2 expression and kappa rearrangements, thus allowing the B cells to express sIgM and to mature
Muraguchi et al., Leukemia & lymphoma 1998 : Among the cytokines, IL-3, IL-6, and IL-7 , but not IL-2, IL-4, SCF, GM-CSF induces RAG activation