◀ Back to BCL2

BCL2 — E2F1

Text-mined interactions from Literome

Lind et al., J Immunol 1999 : Bcl-2 induced changes in E2F regulatory complexes reveal the potential for integrated cell cycle and cell death functions ... Bcl-2 induced changes in E2F complex formation are paralleled by an apparent increase in pRb regulatory activity, by the up-regulation of p130 protein expression, and by the formation of E2F/p130 complexes at the expense of those consisting of E2F/p107
Vairo et al., Mol Cell Biol 2000 : A plausible relevant target of p130/E2F4 is the E2F1 gene, because Bcl-2 expression delayed E2F1 accumulation during G ( 1 ) progression and overexpression of E2F1 overrode the Bcl-2 inhibition
Gomez-Manzano et al., Cancer Res 2001 (Glioma) : Transfer of E2F-1 to human glioma cells results in transcriptional up-regulation of Bcl-2
Eischen et al., Oncogene 2001 (Cell Transformation, Neoplastic) : Blocking p53 activity with mutant p53 did not abrogate E2F-1 induced suppression of Bcl-2
Li et al., Oncogene 2007 (Colonic Neoplasms) : Exogenous E2F1 increased the promoter activity of rat Bcl-2 , except in mutants lacking the E2F1 sites
Morales et al., Apoptosis 2011 (Neoplasms) : The natural diterpene ent-16ß-17a-dihydroxykaurane down-regulates Bcl-2 by disruption of the Ap-2a/Rb transcription activating complex and induces E2F1 up-regulation in MCF-7 cells