Gene interactions and pathways from curated databases and text-mining

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ARSK — FOS

Text-mined interactions from Literome

Chang et al., Exp Cell Res 2002 : This suggests that IL-8 induction by LTbetaR is via TRAFs elicited signaling pathways, including NIK/IKK dependent NF-kappaB activation and ASK/MKK/JNK dependent AP-1 activation
Kumasawa et al., Eur J Pharmacol 2005 : The results showed that LTD ( 4 ) induced AP-1 activation determined by AP-1 dependent luciferase gene activity and ASK1 phosphorylation ... These results indicate that LTD ( 4 ) is capable of inducing AP-1 activation and ASK1 regulates AP-1 activation in LTD ( 4 ) -stimulated airway smooth muscle cells
Li et al., Crit Care Med 2005 : ASK1 inhibition with thioredoxin attenuated high tidal volume ventilation induced MIP-2 messenger RNA expression, MIP-2 protein production, neutrophil migration into the lung, airway epithelial cell apoptosis, activation of JNK, and AP-1 DNA binding
Yu et al., J Immunol 2009 : Furthermore, thrombin mediated AP-1 activation was inhibited by ASK1DN , JNK1/2DN, and SP600125
Seong et al., J Biol Chem 2010 : PDK1 functionally suppresses ASK1 mediated AP-1 transactivation and H ( 2 ) O ( 2 ) -mediated apoptosis in a kinase dependent manner
Liu et al., PloS one 2012 (MAP Kinase Signaling System) : CTGF mediated increase of NF-?B and AP-1 luciferase activity was inhibited by SB203580 and SP600125 or ASK1 shRNA or p38 and JNK mutant