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PTGS1 — SRC
Text-mined interactions from Literome
Park et al., Int J Biochem Cell Biol 2004
(Bone Resorption) :
A novel
Src tyrosine kinase inhibitor, Herbimycin A ( HERB ),
reduced COX-2 mRNA levels as well as PGE ( 2 ) production induced by IL-1beta, TNF-alpha and IL-6 or a combination of IL-1beta, TNF-alpha, IL-6, whereas
COX-1 mRNA levels remained unaffected
Collins et al., J Cell Mol Med 2009
:
SRC was concentration-dependently
inhibited by selective
COX-1 ( SC-560 and FR-122047 ) and COX-2 inhibitors ( NS-398 and LM-1685 ), and by SC-51089, a selective antagonist for the PGE-2 receptor ( EP ) and ICI-192,605 and SQ-29,548, selective antagonists for thromboxane receptors ( TP )