Gene interactions and pathways from curated databases and text-mining

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CNR2 — EPHB2

Text-mined interactions from Literome

Zhao et al., J Biol Chem 2005 (Cell Transformation, Neoplastic) : Whether cannabinoid receptor 2 (CB2) is involved in 2-AG induced ERK activation is still unclear
Franklin et al., Pharmacol Res 2013 : Additionally, inhibition of clathrin mediated endocytosis, ERK1/2 , and the AP-1 transcription factor also prevented the cannabinoid receptor induced upregulation of ß-Arrestin 2 ... The CB(2) receptor mediated upregulation of ß-Arrestin 2 would be mediated , at least in part, by an ERK1/2 dependent activation of AP-1
Franklin et al., J Biol Chem 2013 (MAP Kinase Signaling System) : Our results suggest that sustained activation of CB2 receptors, which up-regulates 5-HT2A receptor signaling, enhances GRK5 expression ; the phosphorylation of CB2 receptors ; and the ß-arrestin 2/ERK interactions