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CDH1 — TNF
Text-mined interactions from Literome
Perry et al., Lab Invest 1999
(Celiac Disease) :
The
effect of
TNF-alpha on
E-cadherin expression was maximal after stimulation for 48 hours and also induced modest reductions in beta-catenin expression
Kawai et al., Gastroenterology 2002
(Neoplasm Invasiveness) :
Activation of Src by
TNF-alpha led to reduced
E-cadherin levels and enhanced invasion of src transfectants
Nwariaku et al., Shock 2002
:
The purpose of our study was to determine the effect of TNFalpha on VE-cadherin cell-surface expression and to identify the signaling pathways involved in
TNF induced changes in
cadherin expression
Carayol et al., Eur Respir J 2002
:
In human bronchial epithelial cells the authors have shown that
tumour necrosis factor (TNF)-alpha induced a significant decrease of
E-cadherin and beta-catenin expression ... Dexamethasone inhibited the effect of
TNF-alpha and
induced a three-fold increase in
E-cadherin expression
Nwariaku et al., Blood 2004
:
We found that
tumor necrosis factor (TNF) caused tyrosine phosphorylation of
VE-cadherin , separation of lateral cell-cell junctions, and intercellular gap formation in human umbilical vein endothelial cell ( HUVEC ) monolayers
Angelini et al., Am J Physiol Lung Cell Mol Physiol 2006
:
PP2 also blocked
TNF-alpha induced tyrosine phosphorylation of
VE-cadherin , gamma-catenin, and p120(ctn)
Vandooren et al., Arthritis Rheum 2008
(Rheumatic Diseases) :
In vitro,
cadherin 11 expression by FLS was consistently
up-regulated by
tumor necrosis factor alpha (TNFalpha) at the protein, but not the messenger RNA, level
Parfiniewicz et al., Acta Pol Pharm 2012
:
However,
TNF-alpha did not
cause such a significant increase in
sE-cadherin level
Jakob et al., J Immunol 1998
:
IL-1 and
TNF-alpha caused a rapid reduction in FSDDC
E-cadherin mRNA levels that preceded the decrease in E-cadherin surface expression