Salkowski et al., Infect Immun 1997
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We compared the ability of LPS and MPL to induce interleukin-10 (IL-10), IL-12 p35, IL-12 p40, gamma interferon ( IFN-gamma ), glucocorticoid receptor ( GR ), IL-1 receptor antagonist (IL-1ra), and inducible nitric oxide synthase mRNA expression in murine peritoneal macrophages
Saha et al., Immunopharmacology 1997
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Similarly, both soluble NOS ( sNOS ) and particulate NOS ( pNOS ) activity were significantly up-regulated by MPL ( p < 0.05 )