Gene interactions and pathways from curated databases and text-mining

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APC — IL8

Text-mined interactions from Literome

Zhong et al., Anesthesiology 2004 (Myocardial Infarction...) : APC with sevoflurane attenuated NF-kappaB activation and reduced the expression of tumor necrosis factor alpha, interleukin 1, intercellular adhesion molecule 1, and inducible nitric oxide synthase
Xue et al., Exp Cell Res 2004 : APC also significantly increased the production of IL-6 and IL-8 and suppressed calcium- and LPS stimulated NF-kappaB activity
Mehrotra et al., Immunology 2004 (Melanoma) : Among the various microenvironmental factors, interleukin-10 (IL-10) exhibits a potent immunosuppressive effect on antigen presenting cells (APC)
Li et al., J Zhejiang Univ Sci B 2006 : APC can further increase the level of IL-6 and IL-8 induced by LPS