◀ Back to IGF1
BMP7 — IGF1
Text-mined interactions from Literome
Im et al., J Biol Chem 2003
:
OP-1 was found to
enhance mRNA levels of IGF-1 and the
IGF-1 receptor, the latter of which appeared to be responsible for the combined effect of IGF-1 and OP-1
Wahdan-Alaswad et al., Cancer Res 2010
(Prostatic Neoplasms) :
Insulin-like growth factor I suppresses
bone morphogenetic protein signaling in prostate cancer cells by activating mTOR signaling
Bozić et al., Coll Antropol 2012
:
We have investigated how
BMP-7 regulates gene expression of BMP-4, Dentin matrix protein-1 (DMP-1),
Insulin-like growth factor-I (IGF-I) and -II ( IGF-II ) in cementoblasts
Yeh et al., Endocrinology 1996
:
Osteogenic protein-1 mediated
insulin-like growth factor gene expression in primary cultures of rat osteoblastic cells
Hayden et al., Endocrinology 1997
(Bone Neoplasms...) :
Osteogenic protein-1 stimulates production of
insulin-like growth factor binding protein-3 nuclear transcripts in human osteosarcoma cells
Yeh et al., J Cell Physiol 1998
:
In conclusion,
OP-1 regulates
IGF-I gene expression at the posttranscriptional level, but regulates IGF-II and IGFBP-5 gene expression at the transcriptional level