◀ Back to STAT1

STAT1 — TNFSF10

Text-mined interactions from Literome

Choi et al., Cancer Res 2003 (Adenocarcinoma...) : Our results demonstrate that IFN-beta induction of apoptosis and the induction of proapoptotic mediator TRAIL is Stat1 dependent
Lei et al., Cancer Biol Ther 2005 (Colorectal Neoplasms) : We and others have previously reported the Stat 1 induction of TRAIL is a crucial step in the IFN-beta induced apoptosis pathway
Papageorgiou et al., Cancer Biol Ther 2007 (Urinary Bladder Neoplasms) : Together, our results demonstrate that IFNalpha induces TRAIL expression via a STAT-1/IRF-1 dependent mechanism in human bladder cancer cells, and this induction of TRAIL plays an important role in IFNalpha induced cell killing
Rani et al., J Interferon Cytokine Res 2007 : TRAIL was not induced by IFN-beta in mutant cell lines U2A, U3A, U4A, U5A, and U6A, which lack, respectively, IFN regulatory factor-9 (IRF-9), Stat1 , Jak1, IFNAR-2.2, and Stat2, indicating transcription factor IFN stimulated gene factor 3 ( ISGF3 ) was essential for the induction of this gene