Gene interactions and pathways from curated databases and text-mining

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IL10 — PDC

Text-mined interactions from Literome

Zou et al., Eur J Immunol 2001 (Adenovirus Infections, Human) : Exogenous IL-10 suppressed PDC type I interferon secretion without reducing PDC viability ... Therefore, monocyte IL-10 regulates PDC type I interferon secretion, and PDC type I interferons inhibit MDC differentiation and function
Duramad et al., Blood 2003 : As the activities of ISS on PDCs are central to many clinical applications of ISS, we have studied the effects of IL-10 on PDC stimulation by 3 distinct classes of ISS
Janke et al., Immunology 2006 : A similar T helper type 1 ( Th1 ) /Th2 pattern of cytokines was generated in both systems, but significantly higher levels of IL-3, IL-4 and IL-10 were induced by PDC
Dolganiuc et al., J Immunol 2006 (Hepatitis C, Chronic...) : We identified CD14+ monocytes as the source of TNF-alpha and IL-10 in the HCV core induced inhibition of PDC IFN-alpha production