Gene interactions and pathways from curated databases and text-mining

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CXCL10 — LEP

Text-mined interactions from Literome

Meier et al., Cytokine 2003 (Obesity) : Leptin strongly enhanced the expression and secretion of the interferon-gamma-inducible protein ( IP-10 ) in a human monocytic cell line, as well as in peripheral blood mononuclear cells ... In summary, we have demonstrated that leptin selectively induces the expression and secretion of IP-10 in human monocytic cells, potentially contributing to the vascular complications associated with hyperleptinemic obesity in humans
Johnston et al., Br J Dermatol 2008 (Chronic Disease...) : In vitro, both leptin and resistin could induce CXCL8 and tumour necrosis factor-alpha production by blood monocytes, and leptin could additionally induce IL-1beta and IL-1 receptor antagonist production