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CXCL10 — LEP
Text-mined interactions from Literome
Meier et al., Cytokine 2003
(Obesity) :
Leptin strongly
enhanced the expression and secretion of the interferon-gamma-inducible protein (
IP-10 ) in a human monocytic cell line, as well as in peripheral blood mononuclear cells ... In summary, we have demonstrated that
leptin selectively
induces the expression and secretion of
IP-10 in human monocytic cells, potentially contributing to the vascular complications associated with hyperleptinemic obesity in humans
Johnston et al., Br J Dermatol 2008
(Chronic Disease...) :
In vitro, both leptin and resistin could induce
CXCL8 and tumour necrosis factor-alpha production by blood monocytes, and
leptin could additionally
induce IL-1beta and IL-1 receptor antagonist production