Gene interactions and pathways from curated databases and text-mining

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EPC1 — TNF

Text-mined interactions from Literome

Grisar et al., Ann Rheum Dis 2007 (Arthritis, Rheumatoid) : Our data indicate that TNF may be at least partly responsible for the reduction of EPC seen in patients with RA
Liu et al., J Vasc Res 2010 (Inflammation) : A20 expression reduced EPC activation by tumor necrosis factor-alpha and interleukin-1beta as determined from changes in vascular cell adhesion molecule 1 and E-selectin expression and decreased monocyte transmigration through a monolayer of EPCs
Chen et al., Cell Prolif 2011 : TNF-a increased EPC apoptosis level, reduced VEGF-R1 and SDF-1 mRNA expression ; tumour necrosis factor-a also reduced iNOS and eNOS in the EPCs