Gene interactions and pathways from curated databases and text-mining
IRF6: top 25 interacting genes (chr1:209958967-209979520)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only IRF6-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with IRF6, not among the Top 25
Other genes interacting with IRF6. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

MAPK7 ▸ MAPK6 ▸ IFNG ▸ EPHB2 ▸ NFKBIA ▸ CCL2 ▸ NOS1 ▸
CD14 ▸ ICAM1 ▸ CPOX ▸ IL4 ▸ JUN ▸ IL18 ▸ IL2 ▸
NOS3 ▸ IL5 ▸ IL13 ▸ FOS ▸ PTBP1 ▸ HNRNPF ▸ PTBP2 ▸
HNRNPH1 ▸ IL33 ▸ IL3 ▸ IL15 ▸ IL21 ▸ IL37 ▸ IL32 ▸
IL19 ▸ IL16 ▸ IL24 ▸ IL22 ▸ IL9 ▸ IL11 ▸ IL31 ▸
IL20 ▸ IL7 ▸ IL26 ▸ IL34 ▸ IL25 ▸ IL27 ▸ TLR2 ▸
CSF2 ▸ MMP9 ▸ AKT1 ▸ AKT2 ▸ AKT3 ▸ SYT1 ▸ AHSA1 ▸
CASP1 ▸ CASP3 ▸ CXCL10 ▸ CASP9 ▸ CASP8 ▸ CASP6 ▸ CASP4 ▸
CASP2 ▸ CASP12 ▸ CASP7 ▸ CASP5 ▸ CASP16 ▸ CASP14 ▸ CASP10 ▸
IFNB1 ▸ VCAM1 ▸ IL1RN ▸ RNF19A ▸ GRAP2 ▸ UMOD ▸ WNK1 ▸
LBP ▸ SELE ▸ TLR3 ▸ TLR9 ▸ HMOX1 ▸ TLR1 ▸ CCL3 ▸
TLR7 ▸ VEGFA ▸ CFP ▸ ANXA6 ▸ CRK ▸ TLR5 ▸ TLR8 ▸
TLR6 ▸ LANCL1 ▸ GPI ▸ TLR10 ▸ STAT1 ▸ CD86 ▸ MMP2 ▸
CD79A ▸ CD40 ▸ MMP1 ▸ HMGB1 ▸ MPO ▸ NOX1 ▸ CHUK ▸
ITGAM ▸ IKBKB ▸ CD80 ▸ POLDIP2 ▸ STAT3 ▸ IRF3 ▸ NOX4 ▸
MMP3 ▸ MIP ▸ MYD88 ▸ MMP13 ▸ TP63 ▸ NOX3 ▸ MUC1 ▸
NOX5 ▸ MUC2 ▸ MMP8 ▸ CA2 ▸ TGFB1 ▸ MMP14 ▸ MMP12 ▸
MMP11 ▸ IRAK1 ▸ MUC7 ▸ CXCL1 ▸ RABEPK ▸ MMP28 ▸ MMP10 ▸
MMP21 ▸ MMP26 ▸ CXCL2 ▸ MUC16 ▸ MMP17 ▸ MMP16 ▸ MMP19 ▸
MMP15 ▸ MMP27 ▸ MMP25 ▸ MUC4 ▸ CD46 ▸ MMP7 ▸ MMP20 ▸
MMP24 ▸ MUC15 ▸ TCF3 ▸ MUC20 ▸ TCF4 ▸ TCF12 ▸ TCF24 ▸
MUC22 ▸ MUC21 ▸ TCF15 ▸ MUC8 ▸ IKBKG ▸ TCF19 ▸ TCF23 ▸
MUC19 ▸ MUC12 ▸ MUC13 ▸ MUC6 ▸ TCF20 ▸ TCF25 ▸ MUC17 ▸
TCF21 ▸ CXCL9 ▸ TCF7 ▸ CDC73 ▸ SERPINE1 ▸ PAF1 ▸ CXCL12 ▸
LEO1 ▸ CTR9 ▸ CXCL11 ▸ WDR61 ▸ LYZ ▸ HLA-DRA ▸ HLA-DRB1 ▸
LEP ▸ CXCL5 ▸ PLA2G4A ▸ CXCL13 ▸ PTGS1 ▸ IRF1 ▸ C1orf228 ▸
SOD1 ▸ CXCL6 ▸ CSF3 ▸ SOD3 ▸ SOD2 ▸ MIPEP ▸ IRAK4 ▸
ITGB2 ▸ CXCL16 ▸ CXCL3 ▸ IL23A ▸ IDO1 ▸ CXCL17 ▸ PI3 ▸
CXCL14 ▸ PGF ▸ HDC ▸ REL ▸ CRH ▸ PIK3R1 ▸ PIK3CA ▸
HGF ▸ PDCD11 ▸ MYLIP ▸ LTB ▸ EGR1 ▸ CD83 ▸ IRAK3 ▸
PLA2G1B ▸ SLC25A10 ▸ SAA1 ▸ SOCS3 ▸ CSF1 ▸ ICAM5 ▸ ICAM2 ▸
ICAM3 ▸ NM ▸ NANOS2 ▸ ICAM4 ▸ INS ▸ IRAK2 ▸ MUC5AC ▸
FAS ▸ ARG1 ▸ NUP43 ▸ TBCE ▸ TNFSF11 ▸ CD4 ▸ BPI ▸
SETD2 ▸ IGF1 ▸ TNPO1 ▸ SOAT1 ▸ CCR2 ▸ SLPI ▸ EDN1 ▸
PTGES ▸ CEBPB ▸ MIF ▸ CAT ▸ CREB1 ▸ FASLG ▸ CREB5 ▸
HDAC1 ▸ CCL4 ▸ CEBPA ▸ DEFB4B ▸ CREB3 ▸ DUSP1 ▸ IRF7 ▸
NCF1 ▸ CCL20 ▸ HDAC2 ▸ CRP ▸ MAP3K8 ▸ ARF4 ▸ MDM1 ▸
ARF6 ▸ SRC ▸ ARF1 ▸ IFI44 ▸ MDM4 ▸ SELP ▸ CD69 ▸
S100A12 ▸ ARF3 ▸ PTX3 ▸ MDM2 ▸ ARF5 ▸ IRF2 ▸ PLG ▸
ARG2 ▸ TNFRSF11B ▸ APOE ▸ PLD4 ▸ PLD5 ▸ RBBP4 ▸ RHOA ▸
PLD3 ▸ PPARG ▸ RAC1 ▸ MTOR ▸ PLD6 ▸ CCR7 ▸ GP6 ▸
NGF ▸ HIF1A ▸ CISH ▸ IRF4 ▸ GP5 ▸ ABCC1 ▸ NFKBIB ▸
IRF8 ▸ PLD1 ▸ GP9 ▸ GP2 ▸ SLC17A5 ▸ PLD2 ▸ CD40LG ▸
NOD2 ▸ APOB ▸ PGD ▸ ALB ▸ CDCA5 ▸ CCR5 ▸ AVP ▸
TRAF6 ▸ PRKCA ▸ CCL5 ▸ AGTR2 ▸ BAX ▸ SERPINB2 ▸ TREM1 ▸
JAK2 ▸ ZFP36 ▸ CORT ▸ MAPKAPK2 ▸ PPARA ▸ BDNF ▸ AHR ▸
HBD ▸ ADAM11 ▸ TIMP1 ▸ GJA1 ▸ IL17D ▸ SP1 ▸ GIT2 ▸
CCND1 ▸ APC ▸ BCL2 ▸ HSPG2 ▸ LPL ▸ F3 ▸ TBK1 ▸
LITAF ▸ ATP5O ▸ FCER2 ▸ IL2RA ▸ SELL ▸ ODC1 ▸ IL1R1 ▸
STS ▸ CAV1 ▸ CXCR4 ▸ PDE4B ▸ IRF5 ▸ LTF ▸ IRF9 ▸
ATF2 ▸ LCN2 ▸ LY96 ▸ CALM3 ▸ PLAU ▸ BCL10 ▸ GNRH1 ▸
LIF ▸ RBBP7 ▸ LYN ▸ IFNA4 ▸ EGFR ▸ CCR6 ▸ NA ▸
SUDS3 ▸ GDNF ▸ IL17A ▸ SPP1 ▸ SLC27A5 ▸ CYP3A ▸ ARID4B ▸
GAL ▸ CSRP1 ▸ MLYCD ▸ CD2 ▸ TNFSF10 ▸ EIF2AK2 ▸ SAP130 ▸
PTK7 ▸ MOCOS ▸ HSPD1 ▸ PTK6 ▸ SAP30 ▸ TNFSF13B ▸ MNAT1 ▸
NCF2 ▸ SIN3A ▸ ADM ▸ P2RX7 ▸ SOCS1 ▸ RAF1 ▸ PRL ▸
TFPI ▸ BTK ▸ ATP8A2 ▸ PTK2 ▸ UCN ▸ CCR3 ▸ IFNA2 ▸
PRDX2 ▸ PARP1 ▸ MT3 ▸ AGTR1 ▸ BCL3 ▸ TP53 ▸ IFNA17 ▸
APP ▸ MSH3 ▸ IFNA6 ▸ ECM1 ▸ CXCR1 ▸ CD44 ▸ FGB ▸
SLC22A3 ▸ NLRP3 ▸ NOTCH1 ▸ IL2RB ▸ IFNA21 ▸ CEBPD ▸ IKBKAP ▸
MAP3K14 ▸ PRG3 ▸ CSE ▸ CCR8 ▸ IFNA5 ▸ ECM2 ▸ TGFB2 ▸
CCR1 ▸ RELB ▸ CEL ▸ CCR9 ▸ ACE ▸ CD8A ▸ IFNA14 ▸
IFNA16 ▸ CCR10 ▸ MOK ▸ LDLR ▸ ETS2 ▸ ACP2 ▸ IFNA13 ▸
CD276 ▸ CRAT ▸ CCR4 ▸ PRG4 ▸ LIPA ▸ JAK1 ▸ RETN ▸
IFNA7 ▸ NEDD9 ▸ IFNA10 ▸ SPHK1 ▸ IFNA8 ▸ ADAM17 ▸ SETBP1 ▸
IFNA1 ▸ STAT5A ▸ GCHFR ▸ MAP2K1 ▸ PHKA2 ▸ PRG2 ▸ EDN2 ▸
NOTCH2 ▸ TGFB3 ▸ CD55 ▸ TNFRSF1A ▸ CAV3 ▸ ALG1 ▸ TNFRSF1B ▸
OLR1 ▸ TNP1 ▸ PTPN11 ▸ GIF ▸ PLIN2 ▸ ATF3 ▸ CXCR2 ▸
SLCO6A1 ▸ FBXO32 ▸ SERPING1 ▸ ABCB1 ▸ LTA ▸ MSH2 ▸ PLAUR ▸
MSH5 ▸ S100A8 ▸ CCL24 ▸ HDAC11 ▸ NOTCH3 ▸ EIF4EBP1 ▸ ABCA1 ▸
WAS ▸ IGFBP3 ▸ NEU1 ▸ TXN ▸ SAA4 ▸ CRYGEP ▸ GHR ▸
TRAM2 ▸ OCLN ▸ TYK2 ▸ MAF ▸ HDAC3 ▸ SH3D19 ▸ TF ▸
NOD1 ▸ APCS ▸ EDN3 ▸ SYK ▸ ANXA1 ▸ CADM1 ▸ SAA2 ▸
PCBD1 ▸ TRAM1 ▸ BCL9 ▸ C9orf3 ▸ THBD ▸ PAM ▸ CAMP ▸
BCL5 ▸ NOTCH4 ▸ TNP2 ▸ MSH6 ▸ BCL6 ▸ F2RL1 ▸ UCP2 ▸
SIGLEC7 ▸ CNR2 ▸ MSH4 ▸ RAC2 ▸ F2R ▸ FGFR3 ▸ ANXA5 ▸
GPX3 ▸ POU2F2 ▸ EPB42 ▸ PRDX1 ▸ CTLA4 ▸ GPX1 ▸ CNP ▸
ADCY9 ▸ SCARB1 ▸ TECR ▸ GATA2 ▸ RPTOR ▸ GPX5 ▸ JAK3 ▸
CHD4 ▸ GAST ▸ FADD ▸ MET ▸ HMGCR ▸ CD38 ▸ SLC2A1 ▸
CTRL ▸ TFRC ▸ CDH13 ▸ GFAP ▸ PLCG1 ▸ POMC ▸ TRAF1 ▸
OXTR ▸ TOLLIP ▸ S11 ▸ CD28 ▸ FXR2 ▸ SIGIRR ▸ PTX4 ▸
GSK3B ▸ JUNB ▸ NAALADL1 ▸ GIT1 ▸ COA3 ▸ PRKAA1 ▸ PRKAG1 ▸
CTSB ▸ CCL18 ▸ CD1A ▸ SMC4 ▸ MARCKS ▸ PRKAB1 ▸ ELAVL1 ▸
NEU2 ▸ AQP5 ▸ GPX6 ▸ ISG15 ▸ EIF4E ▸ GPX8 ▸ SMC3 ▸
COA5 ▸ CAV2 ▸ ARC ▸ MT4 ▸ PGC ▸ S7 ▸ WNT2 ▸
NPPA ▸ CYP2B6 ▸ CIITA ▸ MTA2 ▸ BIRC3 ▸ GPX7 ▸ NEU4 ▸
TSPO ▸ CDC42 ▸ PGP ▸ CES1 ▸ JUND ▸ SMC6 ▸ VIP ▸
SMC5 ▸ FPR1 ▸ IFIT2 ▸ HP ▸ NEU3 ▸ SLC7A2 ▸ COA6 ▸
CETP ▸ SMC2 ▸ CEBPZ ▸ LOX ▸ CD19 ▸ CD8B ▸ TYR ▸
ACHE ▸ PRKAB2 ▸ PRKAG2 ▸ MAP3K7 ▸ UBL3 ▸ FXR1 ▸ DDX58 ▸
AGXT ▸ ACO1 ▸ PLTP ▸ STX1A ▸ A2M ▸ HDAC6 ▸ LPO ▸
NPY4R ▸ S12 ▸ GPX2 ▸ DDIT3 ▸ PPARGC1A ▸ SEC14L2 ▸ PRKAA2 ▸
ALPI ▸ COA4 ▸ UPK3B ▸ PLAT ▸ MRXS5 ▸ CX3CL1 ▸ CYBB ▸
ICOSLG ▸ GPX4 ▸ COA1 ▸ VIPR1 ▸ CCND2 ▸ ITGAX ▸ GATA3 ▸
PARP2 ▸ C1QA ▸ PKD3 ▸ RIPK2 ▸ CPZ ▸ ELANE ▸ HPGDS ▸
TNFSF13 ▸ CAPN14 ▸ WNT5A ▸ ACAN ▸ PECAM1 ▸ FMR1 ▸ ADAMTS5 ▸
FEV ▸ LTC4S ▸ FST ▸ NQO1 ▸ PARP9 ▸ IL13RA1 ▸ BDKRB1 ▸
PRKCB ▸ TBL1XR1 ▸ IL1RAP ▸ FPR2 ▸ NDUFAB1 ▸ PPP2R1A ▸ ADCY8 ▸
MAP2K3 ▸ PLN ▸ GPS2 ▸ CROT ▸ CPP ▸ HDAC8 ▸ BCAP31 ▸
MCOLN1 ▸ NCOR1 ▸ IFN1@ ▸ IRG1 ▸ PRKACG ▸ CAPN2 ▸ TUBGCP2 ▸
ISG20 ▸ RHO ▸ ACSL1 ▸ HDAC10 ▸ RHOB ▸ PRKAR1A ▸ SREBF1 ▸
ADCY4 ▸ CYP4F3 ▸ MCM7 ▸ MCM6 ▸ MCM3 ▸ PARP11 ▸ HCLS1 ▸
APOA1 ▸ GSR ▸ CAPN15 ▸ SLC9A1 ▸ ERP27 ▸ LGALS3 ▸ KITLG ▸
NFKBIZ ▸ NR4A1 ▸ OSM ▸ NCF4 ▸ CD5 ▸ CX3CR1 ▸ CAPN12 ▸
TPX2 ▸ NANOS1 ▸ EPS8 ▸ MST1R ▸ AMBP ▸ PVR ▸ TPGS1 ▸
SDC4 ▸ GLA ▸ TRIM63 ▸ PRKAR2B ▸ FOSL1 ▸ QRICH1 ▸ HDAC7 ▸
DST ▸ MAP2K2 ▸ PGR ▸ RASIP1 ▸ AQP1 ▸ C4BPA ▸ PRDM1 ▸
AQP2 ▸ MUC5B ▸ CTSL ▸ TAT ▸ CAPN13 ▸ SPAG8 ▸ SLC11A2 ▸
MTA1 ▸ PARP8 ▸ CAPN9 ▸ CAPN6 ▸ PDCD2 ▸ ADCY2 ▸ EDNRA ▸
LGALS1 ▸ RNPEP ▸ EPS15 ▸ MBD3 ▸ CCL4L2 ▸ ERF ▸ IGH ▸
SERPINB6 ▸ CLU ▸ S1PR1 ▸ SP100 ▸ RSAD2 ▸ MCM2 ▸ TIMP3 ▸
TXNRD2 ▸ PPP2R2B ▸ IDS ▸ ASS1 ▸ KLK3 ▸ DOK3 ▸ USP14 ▸
REG3A ▸ CADM2 ▸ G6PD ▸ HAMP ▸ KHSRP ▸ CD1D ▸ TPO ▸
PARP16 ▸ MLST8 ▸ ESAM ▸ CORO2A ▸ NPR1 ▸ USP7 ▸ PIR ▸
CADM4 ▸ NTRK1 ▸ MAP2K6 ▸ KLF4 ▸ CNR1 ▸ PRKAR1B ▸ ADCY6 ▸
ERP44 ▸ KCNH4 ▸ LAMP5 ▸ CAPN5 ▸ PRKACB ▸ FCGR1A ▸ CYP4F11 ▸
ETS1 ▸ FOXP3 ▸ AQP8 ▸ CLDN1 ▸ GATA5 ▸ TBL1X ▸ IL2RG ▸
HSP90AA1 ▸ NTF3 ▸ GATA1 ▸ MT-CYB ▸ PRX ▸ GATA4 ▸ SDC2 ▸
CYP4F12 ▸ CTNNB1 ▸ CCL1 ▸ ABL1 ▸ PLA2G7 ▸ CD9 ▸ LAMP3 ▸
PDCD1LG2 ▸ MARCO ▸ ADCY10 ▸ NPY ▸ PARP14 ▸ SLC5A1 ▸ PRDX5 ▸
ADCY3 ▸ KCNMA1 ▸ PTHLH ▸ CES2 ▸ CES3 ▸ CYP1A2 ▸ RPS6KB1 ▸
CAPN10 ▸ CADM3 ▸ QRICH2 ▸ AGT ▸ CD58 ▸ PARP6 ▸ C1QB ▸
CYP4F2 ▸ PLEK ▸ MEPE ▸ PPP2CA ▸ ITGAL ▸ PARP15 ▸ LAMP1 ▸
MCM5 ▸ CAPN7 ▸ P2RX4 ▸ SPHK2 ▸ IL1R2 ▸ PLCG2 ▸ PRTN3 ▸
S1PR3 ▸ FGF21 ▸ ADCY1 ▸ C5AR1 ▸ AQP4 ▸ CAPN11 ▸ PMPCB ▸
PTEN ▸ GALT ▸ SST ▸ HDAC5 ▸ MICE ▸ VDR ▸ HDAC4 ▸
PARP3 ▸ LRP1 ▸ VWF ▸ CAPN8 ▸ PARP12 ▸ IKBKE ▸ EPB41 ▸
FGF2 ▸ PRKAR2A ▸ BCR ▸ AKT1S1 ▸ SMAD4 ▸ TFAP2A ▸ ADCY5 ▸
S100A9 ▸ ITGB1 ▸ MTDH ▸ MCS ▸ INSR ▸ CAPN1 ▸ PPARD ▸
LAMP2 ▸ IL18BP ▸ ADCY7 ▸ PARP10 ▸ CAPN3 ▸ SIRT1 ▸ SMAD7 ▸
ERP29 ▸ TPGS2 ▸ MAL ▸ CYP4F8 ▸ GATA6 ▸ NR1I2 ▸ PDGFA ▸
CYP4F22 ▸ SMN1 ▸ HDAC9 ▸ PDGFB ▸ PKD2 ▸ FGF9 ▸ CYP1A1 ▸
PARP4 ▸ F12 ▸ STAR ▸ PKD1 ▸ IL6R ▸ MCM4 ▸ GPS1 ▸
MID1 ▸ RFX3 ▸ TAF1 ▸ COPS2 ▸ ZBTB3 ▸ COPS5 ▸ UBC ▸
COPS6 ▸ COPS4 ▸ GTF2A1 ▸ BNC2 ▸ CREBBP ▸ TLX2 ▸ CDK4 ▸
ARHGAP29 ▸ NR3C1 ▸ SMARCD1 ▸ PCAF ▸ GTF3A ▸ ONECUT1 ▸ GTF2E1 ▸
Data information
Please see the Gene Interactions Track Manual.