◀ Back to CXCL12
CXCL12 — TGFB1
Text-mined interactions from Literome
Nanki et al., J Immunol 2001
(Arthritis, Rheumatoid) :
On the other hand, CCL2, CCL5, and
CXCL12 were expressed on RA FLS, and their production was
regulated by TNF-alpha, IL-1beta, and
TGF-beta1
Bartolomé et al., Mol Biol Cell 2003
:
Moreover,
TGF-beta1 further increased cell adhesion mediated by alpha4 integrins in
response to the chemokine
stromal cell derived factor-1alpha
Ohira et al., Pathol Int 2006
(Bile Duct Neoplasms...) :
Expression of SDF-1 in cultured fibroblasts was downregulated by TGF-beta1 treatment, and coculture with CC cells and anti-TGF-beta1 neutralizing antibody restored the decreased SDF-1 expression, suggesting that
TGF-beta1 secreted from CC cells might have
reduced the expression of
SDF-1 by fibroblasts and might have reduced the increased invasion of CC cells induced by the supernatant from fibroblasts
Yang et al., Cancer Res 2008
(Adenocarcinoma...) :
In the CAF, we show that BMP2 or BMP7, but not
transforming growth factor beta-1 , can strikingly
stimulate secretion of
stromal cell derived factor-1 (SDF-1) , also known as CXCL12