Fina et al., Eur J Cancer 2006
(Colorectal Neoplasms) :
Although 5-ASA induces dissipation of mitochondrial transmembrane potential and caspase-3 activation, zVAD-fmk does not completely prevent the 5-ASA induced cell death
Leung et al., Dig Dis Sci 2009
(Adenocarcinoma...) :
Our results indicate that ASA in the presence of caspase inhibitors causes gastric mucosal cell death through a caspase independent pathway suggestive of apoptosis-like programmed cell death
Liou et al., Mol Pharmacol 2008
:
ASA and NaS at 1 mM did not induce PARP cleavage or caspase-3 and at 5 mM, ASA but not NaS increased apoptosis