Gene interactions and pathways from curated databases and text-mining

◀ Back to EPHB2

EPHB2 — S1PR1

Text-mined interactions from Literome

O'Brien et al., Arterioscler Thromb Vasc Biol 2007 : Using siRNA, we found that the effect of APC on the EGR-1/ERK signaling required for TRAIL inhibition was dependent on the S1P1 receptor and S1P1 kinase
Miller et al., Mol Cell Biol 2008 (Disease Progression...) : Finally, our data demonstrate that TGFbeta activation of ERK1/2 , as well as induction of migration and invasion, is mediated at least in part by ligation of the S1P receptor, S1PR2
Ryser et al., Mol Immunol 2008 : S1P(1) overexpression resulted in reduced CXCR4 surface expression levels and strong inhibition of SDF-1 dependent ERK1/2 phosphorylation and Ca ( 2+ ) flux
Costello et al., International journal of molecular sciences 2011 : The eosinophil granule protein eosinophil peroxidase (EPO) induced ERK dependent up-regulation of transcription of S1P(1) , LPA ( 1 ), LPA ( 2 ) and LPA ( 3 ), providing the situation whereby eosinophil granule proteins may enhance S1P- and/or LPA- induced eosinophil accumulation at nerve cells in allergic conditions
Duru et al., J Surg Res 2012 (Diabetes Mellitus...) : Down-regulation of S-1-PR1 reduced ERK1/2 activation in response to S-1-P, while that of S-1-PR2 had no effect under normal conditions