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EPHB2 — S1PR1
Text-mined interactions from Literome
O'Brien et al., Arterioscler Thromb Vasc Biol 2007
:
Using siRNA, we found that the effect of APC on the
EGR-1/ERK signaling required for TRAIL inhibition was
dependent on the
S1P1 receptor and S1P1 kinase
Miller et al., Mol Cell Biol 2008
(Disease Progression...) :
Finally, our data demonstrate that TGFbeta activation of
ERK1/2 , as well as induction of migration and invasion, is
mediated at least in part by ligation of the S1P receptor,
S1PR2
Ryser et al., Mol Immunol 2008
:
S1P(1) overexpression
resulted in reduced CXCR4 surface expression levels and strong inhibition of SDF-1 dependent
ERK1/2 phosphorylation and Ca ( 2+ ) flux
Costello et al., International journal of molecular sciences 2011
:
The eosinophil granule protein eosinophil peroxidase (EPO) induced
ERK dependent up-regulation of transcription of
S1P(1) , LPA ( 1 ), LPA ( 2 ) and LPA ( 3 ), providing the situation whereby eosinophil granule proteins may enhance S1P- and/or LPA- induced eosinophil accumulation at nerve cells in allergic conditions
Duru et al., J Surg Res 2012
(Diabetes Mellitus...) :
Down-regulation of
S-1-PR1 reduced
ERK1/2 activation in response to S-1-P, while that of S-1-PR2 had no effect under normal conditions