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BMP2 — WNT5A
Text-mined interactions from Literome
Dai et al., Cancer Res 2008
(Neoplasm Metastasis...) :
Transfection of C4-2B cells with axin, an inhibitor of canonical Wnt signaling, blocked Wnt3a but not
Wnt5a induction of the
BMP promoters ... In contrast, Jnk inhibitor I blocked
Wnt5a but not Wnt3a
induction of the
BMP promoters
Olivares-Navarrete et al., Acta Biomater 2011
:
Wnt5a , but not Wnt3a,
increased MG63 cell differentiation and
BMP2 and BMP4 proteins, suggesting Wnt5a promotes osteogenic differentiation through production of BMPs. Effects of exogenous and endogenous Wnt5a were synergistic with surface microstructure, suggesting the response also depends on cell maturation state