Gene interactions and pathways from curated databases and text-mining

◀ Back to LIF

LIF — POU5F1

Text-mined interactions from Literome

Davey et al., Stem Cells 2006 : ESC colonies demonstrated radial organization of phosphorylated signal transducer and activator of transcription 3, Nanog, and Oct4 ( among others ) in the presence and absence of exogenous leukemia inhibitory factor (LIF)
Debeb et al., PloS one 2009 : Like ES cells, the XEN-P cells express Oct4 and SSEA1 at high levels and their growth is stimulated by leukemia inhibitory factor , but instead of the epiblast determinant Nanog, they express the ExEn determinants Gata6 and Gata4
Singh et al., Biochem Biophys Res Commun 2009 : In the presence of LIF , mES cells adherent to the FIII9'10-dimer showed transient upregulation of Oct-4 , the mesodermal transcription factor, Brachyury, and the ectodermal marker, Nestin
Hall et al., Cell stem cell 2009 : Oct4 primarily induces Klf2 while LIF/Stat3 selectively enhances Klf4 expression
Vizlin-Hodzic et al., Cellular reprogramming 2011 : Depletion of SAF-A decreases Oct4 expression even in the presence of LIF , and results in an increase of the mesodermal marker Brachyury