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AKT3 — FYN
Text-mined interactions from Literome
Ballif et al., Brain Res Mol Brain Res 2003
:
Additionally, although Fyn is an important regulator of Dab1,
Fyn deficiency does not
prevent acute Reelin induced
Akt activation
Wang et al., J Biol Chem 2010
(Wounds and Injuries) :
Engagement of LN332 or clustering of the alpha6beta4 integrin with integrin-specific antibodies causes phosphorylation of ErbB2,
Fyn , and the beta4 subunit as well as
activation of phosphatidylinositol 3-kinase and
Akt and their assimilation into this complex
Yadav et al., Mol Carcinog 2011
:
Fyn is
induced by
Ras/PI3K/Akt signaling and is required for enhanced invasion/migration ... Activation of
Akt , but not MAPK or EGFR, was
necessary and sufficient for induction of
Fyn by H-Ras
Hatton et al., PloS one 2012
(Lymphoma, B-Cell) :
Whereas Src kinases are often required for Syk activation, we show here that
PI3K/Akt activation and autocrine IL-10 production by NGFR-LMP1
involves the Src family kinase
Fyn
Zhang et al., PloS one 2012
(Diabetes Mellitus, Experimental...) :
Zn is required for maintaining Akt activation by inhibiting the expression of Akt negative regulators ;
Akt activation can
inhibit Fyn nuclear translocation to export nuclear Nrf2 to cytoplasm for degradation