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EPHB2 — TRH
Text-mined interactions from Literome
Le Péchon-Vallée et al., Neuroendocrinology 2000
(MAP Kinase Signaling System) :
ERK activation by VIP or PACAP38 and
TRH were additive and both sensitive to the MEK inhibitors PD98059 and U0126
Banihashemi et al., Mol Endocrinol 2002
:
D2S stimulation also decreased
TRH induced
MAPK/ERK kinase phosphorylation
Van-Ham et al., J Neurochem 2007
:
Activation of rat or human dopamine-D ( 2 ) S, muscarinic or somatostatin receptors inhibited
thyrotropin releasing hormone induced
ERK1/2 phosphorylation, while the D ( 2 ) L receptor failed to inhibit this response ... In transfected GH4 cells, the D ( 2 ) L-SS mutant inhibited
thyrotropin releasing hormone induced
ERK1/2 phosphorylation almost as strongly as the D ( 2 ) S receptor
Nafisi et al., J Biol Chem 2008
:
In these clones, D2S mediated inhibition of
TRH induced
phospho-ERK1/2 was reversed by 70-80 % compared with parental GH4ZR7 cells
Mijiddorj et al., Endocr J 2012
:
In addition,
TRH induced
ERK ( Extracelluar signal regulated kinase ) activation was enhanced in the presence of NKB