Gene interactions and pathways from curated databases and text-mining

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E2F1 — TNF

Text-mined interactions from Literome

Carlberg et al., Int J Oncol 1999 : Protein binding assays indicate that TNF and gamma-INF did not effect the ability of the ME1a2 factor to bind to its site but did significantly repress E2F factor binding to its DNA sequence
Kishore et al., Circ Res 2003 : Tumor necrosis factor mediated E2F1 suppression in endothelial cells : differential requirement of c-Jun N-terminal kinase and p38 mitogen activated protein kinase signal transduction pathways ... Taken together, these data suggest a differential requirement of JNK1 and p38 MAPK in TNF regulation of E2F1
Tammali et al., Endocrinology 2010 (Diabetes Mellitus, Experimental) : Treatment of VSMC with AR inhibitor sorbinil prevented HG- as well as TNF-alpha induced phosphorylation of retinoblastoma protein and activation of E2F-1