Gene interactions and pathways from curated databases and text-mining

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IFNG — PSENEN

Text-mined interactions from Literome

Liao et al., J Biol Chem 2004 (MAP Kinase Signaling System) : Using this reporter assay, we have demonstrated that interferon-gamma , interleukin-1beta, and tumor necrosis factor-alpha can specifically stimulate gamma-secretase activity, concomitant with increased production of Abeta and the intracellular domain of APP ( AICD )
Jutras et al., J Biol Chem 2005 (Inflammation) : Finally, our results indicate that interferon-gamma stimulates gamma-secretase dependent cleavages on phagosomes and that gamma-secretase activity may be involved in the phagocytic response of macrophages to inflammatory cytokines