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IFNG — PSENEN
Text-mined interactions from Literome
Liao et al., J Biol Chem 2004
(MAP Kinase Signaling System) :
Using this reporter assay, we have demonstrated that
interferon-gamma , interleukin-1beta, and tumor necrosis factor-alpha can specifically
stimulate gamma-secretase activity, concomitant with increased production of Abeta and the intracellular domain of APP ( AICD )
Jutras et al., J Biol Chem 2005
(Inflammation) :
Finally, our results indicate that
interferon-gamma stimulates gamma-secretase dependent cleavages on phagosomes and that
gamma-secretase activity may be
involved in the phagocytic response of macrophages to inflammatory cytokines