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LIF — RAF1

Text-mined interactions from Literome

Kodama et al., Am J Physiol Heart Circ Physiol 2000 (Cardiomegaly) : LIF sequentially activated Raf-1 , MEK1/2, ERK1/2, and p90 ( RSK )
Arthan et al., Cancer Lett 2010 (Carcinoma, Medullary...) : Ras/Raf/MEK/ERK activation was sufficient to induce growth inhibition and LIF expression in the human MTC line MZ-CRC-1
Schiemann et al., Oncogene 1998 : Although phorbol ester failed to activate Raf-1 directly, a protein kinase C-stimulated signal was found to be necessary, but not sufficient, for LIF mediated activation of Raf-1 ... Elevation of intracellular cAMP levels completely blocked Raf-1 activation by LIF , but was without effect on the magnitude of mitogen activated protein kinase ( MAPK ) stimulation by the cytokine, suggesting the presence of a Raf-1 independent, cAMP-insensitive MAPK kinase kinase ( MAPKKK ) pathway in 3T3-L1 cells