Gene interactions and pathways from curated databases and text-mining

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TNF — TSC22D3

Text-mined interactions from Literome

Yang et al., J Cell Biochem 2008 : Using a retrovirus mediated gene expression approach we demonstrate that overexpression of GILZ inhibits TNF-alpha and IL-1beta induced COX-2 mRNA and protein expression, and knockdown of GILZ by shRNA reduces glucocorticoid inhibition of cytokine induced COX-2 expression
Zhang et al., Clin Exp Allergy 2009 (Chronic Disease...) : IL-1beta, TNF-alpha , IL-4, and IL-13 reduced, whereas IFN-gamma enhanced GILZ mRNA levels in the sinonasal mucosa
Beaulieu et al., Arthritis Rheum 2010 (Arthritis, Experimental) : Depleting GILZ expression in vivo increased the clinical and histologic severity of CIA and increased synovial expression of tumor necrosis factor and interleukin-1 (IL-1), without affecting the levels of circulating cytokines or anticollagen antibodies
Cheng et al., J Immunol 2013 (MAP Kinase Signaling System) : Experiments in a human microvascular endothelial cell line demonstrated that TNF-inducible NF-?B activity was significantly inhibited by overexpression of GILZ