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TNF — TSC22D3
Text-mined interactions from Literome
Yang et al., J Cell Biochem 2008
:
Using a retrovirus mediated gene expression approach we demonstrate that overexpression of
GILZ inhibits
TNF-alpha and IL-1beta induced COX-2 mRNA and protein expression, and knockdown of GILZ by shRNA reduces glucocorticoid inhibition of cytokine induced COX-2 expression
Zhang et al., Clin Exp Allergy 2009
(Chronic Disease...) :
IL-1beta,
TNF-alpha , IL-4, and IL-13 reduced, whereas IFN-gamma
enhanced GILZ mRNA levels in the sinonasal mucosa
Beaulieu et al., Arthritis Rheum 2010
(Arthritis, Experimental) :
Depleting
GILZ expression in vivo increased the clinical and histologic severity of CIA and
increased synovial expression of
tumor necrosis factor and interleukin-1 (IL-1), without affecting the levels of circulating cytokines or anticollagen antibodies
Cheng et al., J Immunol 2013
(MAP Kinase Signaling System) :
Experiments in a human microvascular endothelial cell line demonstrated that
TNF-inducible NF-?B activity was significantly
inhibited by overexpression of
GILZ