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CCL11 — TNF

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: CCL11 → TNF (increases)
  Evidence: An ELISA assay was used to quantitatively evaluate eotaxin protein expression. This analysis demonstrated marked induction of eotaxin protein expression by aortic smooth muscle cells after treatment with TNF-a, whereas untreated control cells did not show eotaxin protein expression (P,0.001) (Figure 1).

Text-mined interactions from Literome

Stellato et al., J Immunol 1999 : Eotaxin and MCP-4 mRNA expression induced by TNF-alpha alone or in combination with IFN-gamma was near-maximal after 1 h, peaked at 4 and 8 h, respectively, remained unchanged up to 24 h, and was protein synthesis independent
Katayama et al., Am J Respir Cell Mol Biol 2002 : Eotaxin was induced by tumor necrosis factor (TNF)-alpha or interleukin (IL)-4 and was drastically increased by their combination
Banwell et al., Cytokine 2002 : Unlike Eotaxin-1, Eotaxin-3 mRNA expression was not induced by either tumour necrosis factor (TNF)-alpha or interleukin (IL)-1 beta alone
Lee et al., Br J Pharmacol 2006 : Rosmarinic acid as a downstream inhibitor of IKK-beta in TNF-alpha induced upregulation of CCL11 and CCR3 ... 2. In order to determine the effects of rosmarinic acid on the TNF-alpha induced upregulation of CCL11 and CCR3 in human dermal fibroblasts, we performed an enzyme linked immunosorbent assay for CCL11 and a Western blot assay for CCR3 ... The TNF-alpha induced expression of CCL11 and CCR3 genes was attenuated by rosmarinic acid
Rokudai et al., Biol Pharm Bull 2006 (Asthma...) : Differential regulation of eotaxin-1/CCL11 and eotaxin-3/CCL26 production by the TNF-alpha and IL-4 stimulated human lung fibroblast
Clarke et al., J Immunol 2008 : In this study, we describe a novel role for protein kinase C ( PKC ) betaIotaIota in augmenting NF-kappaB mediated TNF-alpha induced transcription of the target gene CCL11 in human airway smooth muscle cells by phosphorylating the HAT p/CAF ... Furthermore, mouse embryonic fibroblasts from PKCbeta knockout mice showed markedly reduced TNF-alpha induced CCL11 expression and NF-kappaB reporter activity that was restored on PKCbetaII overexpression, suggesting a critical role for this pathway
Hosokawa et al., Cell Physiol Biochem 2013 : Moreover, we examined the effects of EGCG on CCL11 production in HGFs. Methods and Results : ELISA analysis disclosed that interleukin (IL)-4 synergistically enhanced CCL11 production in IL-1ß or tumor necrosis factor (TNF)-a stimulated HGFs. EGCG prevented IL-1ß/ IL-4 or TNF-a/IL-4 mediated CCL11 production in a concentration dependent manner