Gene interactions and pathways from curated databases and text-mining

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CX3CL1 — MAPK8

Text-mined interactions from Literome

Brand et al., Gastroenterology 2002 (MAP Kinase Signaling System...) : Fractalkine mediated the MEK-1 and G alpha i-dependent but phosphatidylinositol-3-kinase independent activation of extracellular signal regulated kinase-MAPK
Ralay Ranaivo et al., Brain Res 2010 (MAP Kinase Signaling System) : Albumin activated ERK1/2, p38 MAPK and JNK signaling pathways in astrocytes, and induced the production of interleukin (IL)-1beta, inducible nitric oxide (NO) synthase, the NO metabolite nitrite, and the chemokine CX3CL1 while reducing the level of S100B
Clements et al., J Immunol 2010 (Angiomyolipoma...) : In AML cells, their ligands CXCL12 CX3CL1 , CCL11, CCL24, and CCL28 caused robust phosphorylation of p42/44 MAPK and Akt
Park et al., Transplant Proc 2012 (MAP Kinase Signaling System) : Fractalkine ( 50 ng/mL ) also induced cellular ROS production and activation of ERK1/2 and p38 MAPK in mesangial cells
Gan et al., Cell Tissue Res 2013 (Inflammation) : Inhibitors of p38MAPK , JAK-STAT, NF-kB, and AP-1 significantly reduced CX3CL1 and CX3CR1 expression