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SMAD7 — SMN1

Text-mined interactions from Literome

Subramanian et al., Mol Biol Cell 2004 : A novel Sp1 : Pur : SPUR complex was dissociated when SMA enhancer activity was increased by TGFbeta1 or Smad protein overexpression
Gu et al., Acta Pharmacol Sin 2007 : We found that the overexpression of Smad3, not Smad2 markedly increased ( TGF)-beta(1 ) -induced alpha-SMA promoter activity and alpha-SMA protein expression in vitro, whereas the overexpression of dominant negative mutant Smad3 and Smad7 repressed ( TGF)-beta(1 ) -induced alpha-SMA gene expression
Wang et al., Zhong Nan Da Xue Xue Bao Yi Xue Ban 2009 (Fibrosis...) : Compared with the UUO group, the degree of renal interstitial lesion and the expression of TGF-beta1 mRNA, CTGF mRNA, alpha-SMA and CTGF were decreased, but the expression of Smad7 increased in the treatment group
Song et al., Exp Mol Med 2010 (Arthritis, Rheumatoid) : Small interfering RNA mediated silencing of Smad2 or adenoviral overexpression of Smad7 ( an inhibitory Smad isoform ) completely inhibited RA-SF stimulated alpha-SMA expression
Wang et al., Med Sci Monit 2012 (Disease Progression...) : Over-expression of Smad7 and uPA inhibited the expression of a-SMA and TGF- ß1 significantly