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RAC1 — SDC1

Text-mined interactions from Literome

Park et al., Cancer Res 2005 (Fibrosarcoma...) : Consistent with the increased cell migration/invasion of syndecan-2 overexpressing HT1080 cells, syndecan-2 overexpression increased phosphorylation and interaction of focal adhesion kinase ( FAK ) and phosphatidylinositol 3-kinase (PI3K), membrane localization of T-lymphoma invasion and metastasis gene-1 ( Tiam-1 ), and activation of Rac
Bass et al., J Cell Biol 2007 : In wild-type fibroblasts, syndecan-4 mediates the matrix induced protein kinase Calpha (PKCalpha) dependent activation of Rac1 and localizes Rac1 activity and membrane protrusion to the leading edge of the cell, resulting in persistent migration