Gene interactions and pathways from curated databases and text-mining

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HSP90AA1 — IL6

Text-mined interactions from Literome

Stephanou et al., Gene Expr 1999 : We have previously demonstrated that interleukin-6 (IL-6) increases the levels of the heat shock protein 90 (Hsp90) and activates the Hsp90beta promoter via the IL-6 activated transcription factors NF-IL6 and STAT-3 ... The effect of IL-6/STAT-3 and IFN-gamma/STAT-1 was mediated via a short region of the Hsp70/Hsp90 promoters, which also mediates the effects of NF-IL6
Kanzaki et al., Biochem Biophys Res Commun 2003 : Telomerase upregulates expression levels of interleukin (IL)-1alpha, IL-1beta, IL-6 , IL-8, and granulocyte-macrophage colony stimulating factor in normal human fibroblasts
Stephanou et al., J Biol Chem 1999 : We have previously demonstrated that interleukin-6 (IL-6) increases the levels of the heat shock protein 90 (Hsp-90) and activates the Hsp-90beta promoter via the IL-6 activated transcription factors NF-IL6 and signal transducer and activator of transcription-3 ( STAT-3 ) ... The effect of IFN-gamma/STAT-1 was mediated via a short region of the Hsp-70/Hsp-90 promoters, which also mediates the effects of NF-IL6 and STAT-3 and can bind STAT-1