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CASP10 — MEFV
Text-mined interactions from Literome
Tang et al., J Neurosci 2005
:
Destabilization of MEF2 is caused by an increase in
caspase dependent cleavage of
MEF2
Chae et al., Proc Natl Acad Sci U S A 2006
(Familial Mediterranean Fever) :
Pyrin , the protein mutated in FMF,
regulates caspase-1 activation and consequently IL-1beta production through cognate interaction of its N-terminal PYRIN motif with the ASC adaptor protein
Roldan et al., Joint Bone Spine 2008
(Familial Mediterranean Fever) :
Pyrin , the protein mutated in FMF,
regulates caspase-1 activation and consequently IL-1beta production
Chae et al., Br J Haematol 2009
(Familial Mediterranean Fever) :
Pyrin regulates
caspase-1 activation and consequently interleukin-1beta production through the interactions of its N-terminal PYRIN domain and C-terminal B30.2 domain with an adaptor protein, apoptosis associated speck-like protein with a caspase-recruitment domain (ASC) and caspase-1 respectively