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ELAVL1 — MYC

Text-mined interactions from Literome

Kim et al., Genes Dev 2009 : Here, we show that the RBP HuR reduced c-Myc expression by associating with the c-Myc 3 ' untranslated region ( UTR ) next to a miRNA let-7 binding site ... Unexpectedly, HuR and let-7 repressed c-Myc through an interdependent mechanism, as let-7 required HuR to reduce c-Myc expression and HuR required let-7 to inhibit c-Myc expression ... Our findings suggest a regulatory paradigm wherein HuR inhibits c-Myc expression by recruiting let-7 loaded RISC ( RNA miRNA induced silencing complex ) to the c-Myc 3'UTR
Talwar et al., J Biol Chem 2011 (Carcinoma, Squamous Cell...) : Caspase mediated cleavage of RNA binding protein HuR regulates c-Myc protein expression after hypoxic stress
Perrone et al., J Surg Res 2012 : Bile salts increase epithelial cell proliferation through HuR induced c-Myc expression