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IL6 — RAC1

Text-mined interactions from Literome

Faruqi et al., Proc Natl Acad Sci U S A 2001 : Rac1 mediates STAT3 activation by autocrine IL-6 ... Rac V12 expression results in the induction of the IL-6 and IL-6 receptor genes and neutralizing antibodies directed against the IL-6 receptor block Rac1 induced STAT3 activation ... Rac V12 expression results in the induction of the IL-6 and IL-6 receptor genes and neutralizing antibodies directed against the IL-6 receptor block Rac1 induced STAT3 activation
Montaner et al., Blood 2004 (Sarcoma, Kaposi) : Inhibition of Rac1 blocked vGPCR induced transcription and secretion of KS cytokines, including interleukin-6 (IL-6) , IL-8, and growth regulated oncogene alpha ( GROalpha ), in vitro and reduced vGPCR tumorigenesis in vivo