◀ Back to ANGPT2

ANGPT2 — NOS1

Text-mined interactions from Literome

Moreno et al., Am J Physiol Regul Integr Comp Physiol 2002 : The aim of this study was to assess the effects of acute or prolonged increases of ANG II on nitric oxide synthase (NOS) activities and protein expression in mesenteric resistance vessels, left ventricle, renal cortex, and renal medulla ... Acute ANG II infusion increased ( P < 0.05 ) Ca2+ dependent NOS activity in renal cortex and renal medulla ( 81 +/- 18 and 611 +/- 48, respectively ), but no differences were found in mesenteric arteries and left ventricle with respect to control rats
Campese et al., Hypertension 2002 : This raises the possibility that the stimulatory effects of Ang II on central SNS activity may be mediated by inhibition of nNOS and IL-1beta ... In conclusion, these studies suggest that Ang II inhibits the expression of IL-1beta and nNOS in the brain
Fernandez et al., Hypertension 2005 : In Ca ( 2+ ) -loaded neurons, Ang II-induced decreases in [ Ca ( 2+ ) ] i were attenuated by phospholipase C inhibition ( U73122 ) or nitric oxide ( NO ) synthase inhibition ( L-NMMA ) and were mimicked by the cGMP analogue 8-Br-cGMP
Ratliff et al., Pediatr Res 2010 : ANG II regulates nNOS and eNOS expression and NOS activity in afferent arterioles of the developing kidney via AT1 and AT2 receptors
Kim et al., Am J Physiol Endocrinol Metab 2012 : Activation of mTOR/p70S6 kinase by ANG II inhibits insulin stimulated endothelial nitric oxide synthase and vasodilation
Boulanger et al., Circ Res 1998 (Hypertension) : In further support of NOS activation by Ang II in nonendothelial cells, Ang II but not acetylcholine stimulated cGMP levels by 2-fold in SHR arteries without endothelium ; nitro-L-arginine decreased both basal and Ang II-stimulated cGMP levels