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AHSA1 — SMAD2

Text-mined interactions from Literome

Jono et al., J Biol Chem 2003 : Activation of TGF-beta-Smad signaling, however, leads to down-regulation of p38 by inducing MAPK phophatase-1, thereby acting as a negative regulator for MUC5AC induction
Kamaraju et al., J Biol Chem 2005 (Breast Neoplasms...) : We show that Smad2/3 are indispensable for TGF-beta mediated growth inhibition, and that both p38 and Rho/ROCK pathways affect the linker region phosphorylation of Smad2/3
Lu et al., J Appl Physiol 2006 : Transforming growth factor-beta1 induced endothelial barrier dysfunction involves Smad2 dependent p38 activation and subsequent RhoA activation ... We assessed the role of Smad2 in p38 activation and the role of p38 in RhoA activation by TGF-beta1 ... Our data indicate that TGF-beta1 induces endothelial barrier dysfunction involving Smad2 dependent p38 activation, resulting in RhoA activation by possible transcriptional regulation