Gene interactions and pathways from curated databases and text-mining

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ERBB2 — MYLIP

Text-mined interactions from Literome

Epis et al., J Biol Chem 2009 (Prostatic Neoplasms) : miR-331-3p regulates ERBB-2 expression and androgen receptor signaling in prostate cancer
Nishida et al., Clin Cancer Res 2011 (Carcinoma...) : The regulation of ERBB2 by miR-125a-5p was examined with precursor miR-125a transfected cells
Shang et al., Med Sci Monit 2012 (Endometrial Neoplasms...) : RNA interference technology was used to confirm that the invasion inhibition of miR-125b was directly induced by ERBB2
Momose et al., Genes Cells 2013 : miR-214 and hypoxia down-regulate Necl-2/CADM1 and enhance ErbB2/ErbB3 signaling ... miR-214 , that is frequently up-regulated in a variety of cancers, targeted the 3'UTR of the Necl-2 mRNA directly, suppressed the translation of Necl-2 and enhanced the ligand induced ErbB2/ErbB3 signaling in human colon cancer Caco-2 cells ... These results indicate that miR-214 and hypoxia are novel regulators that down-regulate Necl-2 and enhance ErbB2/ErbB3 signaling
Minami et al., J Biol Chem 2013 (Lung Neoplasms) : In addition, miR-199a enhanced the HRG induced ErbB2/ErbB3 signaling ... These results indicate that the suppressive role of Necl-2 in the HRG induced ErbB2/ErbB3 signaling is regulated by miR-199a at least through the reduction of the ST6GAL1 catalyzed sialylation of Necl-2 and/or through the reduction of the protein level of Necl-2 presumably by the protein degradation