Gene interactions and pathways from curated databases and text-mining

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IFNG — RBBP7

Text-mined interactions from Literome

Osborne et al., Mol Cell Biol 2001 : These findings represent the first evidence that HDAC activity can repress IFN-gamma-inducible HLA class II gene expression and also demonstrate that HDAC activity can contribute to promoter repression following the establishment of a DNase I-hypersensitive chromatin conformation
Guo et al., Mol Cells 2006 : Our data indicate that IFNgamma and STAT dependent gene transcription requires the participation of HDAC , as does the IFNalpha-STAT pathway
Keslacy et al., Mol Pharmacol 2007 (Inflammation) : It is noteworthy that IFNgamma decreases TNFalpha induced histone acetyl transferase ( HAT ) and increases histone deacetylase (HDAC) activities
Choi et al., J Immunol 2009 : Importantly, histone deacetylase (HDAC) inhibitors significantly enhanced IFN-gamma-inducible gene expression in trophoblast cells, but not fibroblasts ... We propose that HDAC mediated inhibition of IFN-gamma-inducible gene expression in mouse trophoblast cells may contribute to successful pregnancy by preventing activation of IFN-gamma responses that might otherwise facilitate the destruction of the placenta