◀ Back to CD40
CD40 — IL5
Text-mined interactions from Literome
Bartholomé et al., J Interferon Cytokine Res 1999
:
IFN-beta interferes with the differentiation of dendritic cells from peripheral blood mononuclear cells : selective inhibition of
CD40 dependent
interleukin-12 secretion
Kitagawa et al., Arthritis Rheum 1999
(Arthritis, Rheumatoid) :
Differential
regulation of rheumatoid synovial cell
interleukin-12 production by tumor necrosis factor alpha and
CD40 signals
Muraille et al., Blood 1999
:
Anti-CD3epsilon treatment was found to induce a selective deficiency in the ability of spleen cells to produce bioactive
interleukin-12 in
response to
CD40 stimulation
Tang et al., J Allergy Clin Immunol 2001
(Asthma...) :
The aim of the present study was to define the
roles of B7 and
CD40 costimulatory signals delivered by AMs in regulating T-cell
IL-5 responses in an allergen stimulated coculture system
Reider et al., J Allergy Clin Immunol 2002
(Hypersensitivity) :
Production of IL-4,
IL-5 , IL-10, IL-12, and IL-13 in
response to
CD40 ligation was measured with ELISA
Cattaruzza et al., J Biol Chem 2003
:
Interleukin-10 induction of nitric-oxide synthase expression attenuates
CD40 mediated
interleukin-12 synthesis in human endothelial cells
Moon et al., J Immunol 2004
(IgA Deficiency...) :
IL-5 stimulation of wild-type B-1 cells, but not IL-5Ralpha ( -/- ) B-1 cells,
enhances CD40 expression and augments IgM and IgG production after stimulation with anti-CD40 mAb
Pinzon-Charry et al., Neoplasia (New York, N.Y.) 2005
(Adenocarcinoma...) :
Importantly, despite DR ( + ) IC 's poor responsiveness to inflammatory factors, in samples from healthy volunteers and breast cancer patients,
CD40 ligation
induced phenotypic maturation and
interleukin 12 secretion, in turn generating more efficient T-cell responses
Zhou et al., J Immunol 2007
:
Iloprost and cicaprost also suppressed LPS induced expression of CD86,
CD40 , and MHC class II molecules by BMDCs and
inhibited the ability of BMDCs to stimulate Ag-specific CD4 T cell proliferation and production of
IL-5 and IL-13
Danese et al., Gut 2007
(Colitis...) :
Engagement of
CD40 on HIFs
promoted the release of vascular endothelial growth factor ( VEGF ),
interleukin-8 (IL-8) and hepatocyte growth factor (HGF)
Bose et al., Hum Immunol 2007
(Carcinoma, Squamous Cell...) :
Natural killer cell mediated cytotoxicity of tumor cells initiated by neem leaf preparation is associated with
CD40-CD40L mediated endogenous production of
interleukin-12
Burdin et al., J Immunol 1995
:
First, both
CD40 and Ag receptor ( AgR ) cross linking
induced purified tonsillar human B lymphocytes to secrete the same pattern of cytokines, including IL-1 beta, IL-6, IL-10, granulocyte-macrophage-CSF, and TNF-alpha, whereas IL-1 alpha, IL-2, IL-3, IL-4,
IL-5 , IL-7, granulocyte (G)-CSF, or IFN-gamma were not detected
Kennedy et al., Eur J Immunol 1996
:
CD40/CD40 ligand interactions are
required for T cell dependent production of
interleukin-12 by mouse macrophages
Cella et al., J Exp Med 1996
:
Ligation of
CD40 on dendritic cells
triggers production of high levels of
interleukin-12 and enhances T cell stimulatory capacity : T-T help via APC activation
Peng et al., Eur J Immunol 1996
:
In this study we demonstrate that upon stimulation of human peripheral blood T cells through the T cell receptor (TCR)/CD3 complex,
CD40/CD40L interaction strongly
enhances the production of Th1 cytokines such as interleukin (IL)-2 and interferon (IFN)-gamma and Th2 cytokines such as IL-4,
IL-5 and IL-10 by a direct effect on T cells ... In this study we demonstrate that upon stimulation of human peripheral blood T cells through the T cell receptor (TCR)/CD3 complex,
CD40/CD40L interaction strongly
enhances the production of Th1 cytokines such as interleukin (IL)-2 and interferon (IFN)-gamma and Th2 cytokines such as IL-4,
IL-5 and IL-10 by a direct effect on T cells
Yoshimoto et al., Eur J Immunol 1997
:
Induction of
interleukin-12 p40 transcript by
CD40 ligation via activation of nuclear factor-kappaB
Séguin et al., J Infect Dis 1999
:
Sensitized lymphocytes and
CD40 ligation
augment interleukin-12 production by human dendritic cells in response to Toxoplasma gondii