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NFKB1 — SAA1

Text-mined interactions from Literome

Ray et al., J Immunol 1999 (Acute Disease...) : Persistent expression of serum amyloid A during experimentally induced chronic inflammatory condition in rabbit involves differential activation of SAF, NF-kappa B , and C/EBP transcription factors ... This result suggested that C/EBP, SAF, and NF-kappa B are required for transient acute phase induction of SAA whereas SAF and NF-kappa B activities are necessary for persistent SAA expression during chronic inflammatory conditions
Sodin-Semrl et al., Int J Immunopathol Pharmacol 2004 (Arthritis, Rheumatoid) : Opposing regulation of interleukin-8 and NF-kappaB responses by lipoxin A4 and serum amyloid A via the common lipoxin A receptor ... SAA up-regulated NF-kappaB and AP-1 DNA binding activity, while LXA4 markedly inhibited these responses after IL-1beta stimulation
Jijon et al., Eur J Immunol 2005 : Human HT-29 and Caco-2 monolayers were stimulated with recombinant SAA and NF-kappaB activation/NF-kappaB dependent gene expression measured ... SAA induced IkappaB-alpha degradation, RelA serine 536 ( S536 ) phosphorylation, NF-kappaB transcriptional activity, RelA recruitment to the IL-8 gene promoter and endogenous gene expression ( IL-8, COX-2 ) in HT-29 cells ... Further, Ad5IkappaBAA abrogated SAA induced RelA nuclear translocation, NF-kappaB transcriptional activity and IL-8 gene expression
Lee et al., Biochem Biophys Res Commun 2005 : SAA stimulated the activation of nuclear factor kappaB (NF-kappaB) , which was required for the MMP-9 upregulation by SAA
Mullan et al., Arthritis Rheum 2006 (Arthritis, Rheumatoid...) : Furthermore, A-SAA induced IkappaBalpha degradation and NF-kappaB translocation, suggesting that its proinflammatory effects are mediated in part by NF-kappaB signaling
Okamoto et al., J Rheumatol 2008 (Arthritis, Rheumatoid) : Nuclear factor-kappaB (NF-kappaB) activation by SAA was evaluated by luciferase assay ... Effects of preincubation of soluble RAGE on NF-kappaB activation by SAA was evaluated by Western blotting of IkappaBalpha ... SAA stimulated the transcriptional activation by NF-kappaB in a dose dependent manner and induced expression of the proinflammatory cytokines interleukin 6 (IL-6) and IL-8 ... SAA stimulation promoted nuclear translocation of NF-kappaB , whereas preincubation of SAA with RAGE inhibited nuclear translocation
Hiratsuka et al., Nat Cell Biol 2008 (Neoplasm Metastasis...) : In our study, SAA3 stimulated NF-kappaB signalling in a TLR4 dependent manner and facilitated metastasis
Lee et al., Biochem Biophys Res Commun 2009 (Atherosclerosis) : SAA induced the activations of NF-kappaB and AP-1, which were essential for CCL2 production after SAA stimulation
Chen et al., Am J Respir Crit Care Med 2010 (Disease Models, Animal...) : The effect of serum amyloid A on nuclear factor (NF)-kappaB induction, cytokine expression, and Toll-like receptor-2 stimulation was determined with transformed human cell lines and bronchoalveolar lavage cells from patients with sarcoidosis
Betts et al., J Biol Chem 1993 : The role of NF-kappa B and NF-IL6 transactivating factors in the synergistic activation of human serum amyloid A gene expression by interleukin-1 and interleukin-6