Gene interactions and pathways from curated databases and text-mining

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HDAC3 — HLA-DRB1

Text-mined interactions from Literome

Chou et al., Mol Immunol 2008 : We have previously reported that Major Histocompatibility Complex ( MHC) class II can be induced by histone deacetylase inhibitors ( HDACi ) in the absence of class II transactivator (CIITA)
Bagci-Onder et al., Oncogene 2013 (Glioblastoma) : A histone deacetylase inhibitor, MS-275, resulted in upregulation of DR4/5 in all GBM cell lines, and these changes could be followed in real time both in vitro and in vivo in mice bearing tumors and they correlated with increased TRAIL sensitivity