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ELF3 — IL8

Text-mined interactions from Literome

McElvaney et al., J Clin Invest 1992 (Cystic Fibrosis...) : Human bronchial epithelial cells exposed to CF ELF recovered before rSLPI therapy expressed IL-8 mRNA transcripts, but ELF recovered after rSLPI therapy induced far less bronchial epithelial cell IL-8 gene expression
Wang et al., J Biol Chem 2004 : Moreover, the induction of ESE-1 in response to inflammatory cytokine interleukin-1 is associated with a parallel increase of the expression of p300 in vascular endothelial cells, suggesting that in the setting of inflammation, the transcriptional activity of ESE-1 is positively modulated by interaction with the transcriptional co-activator p300
Nakamura et al., J Clin Invest 1992 (Cystic Fibrosis) : CF ELF contained high levels of neutrophil elastase ( NE ) and various serine protease inhibitors prevented CF ELF from inducing IL-8 gene expression in BET-1A cells, suggesting that NE was the dominant inducer for IL-8 production in CF ELF