Gene interactions and pathways from curated databases and text-mining

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CYP2B6 — PPARA

Text-mined interactions from Literome

Shaban et al., Xenobiotica 2005 : To the best of the authors ' knowledge, this is the first study showing the presence of mutual effects of AhR and PPARalpha on CYP2B and CYP3A and an additive inhibitory effect on CYP2C11 in the livers of male rats
Wieneke et al., FEBS Lett 2007 (Starvation) : The PPARalpha dependent increase in CAR potentiated the phenobarbital induced transcription of the prototypical CAR dependent gene CYP2B1